THE BIOMAĒ+ PROTOCOL
The daily microbiome
protocol.
Twelve weeks to terrain.
The Biomaē+ protocol is not a supplement routine. It is a structured recolonisation programme — designed around the documented colonisation timelines of twelve characterised strains, and built for one purpose: to help your microbiome rebuild itself.
01
Consistencyover intensity
A single capsule, same time daily, outperforms any high-dose short course. The strains need repeated exposure to establish. Skipping days resets the process.
02
Contextmatters
What you eat, how you sleep, and your stress environment are as important as the capsule itself. The formula works within your terrain — it doesn't override it.
03
The arcis long
Microbiome composition shifts over weeks, not days. Published colonization data for our strains shows measurable change at 4 weeks, more significant change at 8–12. Patience is part of the protocol.
01 / THE DAILY PRACTICE
Two capsules.
Same time.
Every day.
Biomaē+ Daily is designed for morning use — taken with or without food, with a full glass of water. The acid-resistant capsule bypasses stomach acid regardless of when you take it, but morning use integrates more naturally into a consistent routine.
The capsules do not require refrigeration. They are formulated for ambient stability, which means travel, office, and routine disruption are not obstacles.
DAILY RITUAL
TIME
Morning — with or without food
DOSE
2 capsules
WATER
Full glass — 250ml minimum
STORAGE
Ambient — no refrigeration needed
TIP
Pair with an existing morning habit — coffee, breakfast, supplements you already take.
02 / THE COLONIZATION TIMELINE
What the research shows.
Based on published clinical data for the characterized strains in Biomaē+ Daily.
Week 1–2
Initial transit
Strains begin passing through the gut. Some initial shifts in transit regularity are common — this is the terrain adjusting, not a side effect.
Week 3–4
Early colonization
Documented strains begin establishing at their primary colonization sites. This is when the protocol begins to take root.
Week 5–8
Consolidation
Strain populations stabilize. The coordinated protocol begins to function as a system rather than isolated populations.
Week 9–12
Establishment
Published data for our characterized strains shows the most significant microbiome composition shifts in this window. This is the payoff of consistency.
† Individual results are not guaranteed and will vary. These timelines reflect clinical research for individual strains, not clinical trials of Biomaē+ formulas.
03 / TERRAIN FACTORS
The capsule works within your terrain.
These factors shape the terrain.
What helps
Diverse whole plant foods
Fibre is substrate for your strains — variety matters more than volume.
Fermented foods alongside
Kimchi, kefir, miso — additive, not replacements.
Consistent sleep
Circadian rhythm affects microbiome composition measurably.
Hydration
Capsule transport and intestinal environment both depend on it.
Time
The most important factor.
What works against it
Antibiotic courses
Necessary when needed — resume the protocol after the course ends.
High ultra-processed food intake
Reduces microbial diversity over time — the opposite of what we're building.
Chronic stress
The gut-brain axis runs in both directions.
Inconsistency
Skipping days during the critical colonization window slows the process.
Expecting speed
The terrain is not impatient. Neither should the protocol be.
"We are not telling you to change your life. We are telling you what the research shows influences your terrain. Use this information as context, not instruction."
"Cultivate rather than combat. The terrain is everything."
— THE BIOMAĒ+ PHILOSOPHY
04 / FIND YOUR FORMULA
The protocol is the same.
The formula is personal.
All five Biomaē+ formulas follow the same daily protocol — two capsules, same time, every day. The difference is in which strains are prioritized for your microbiome goals.
DAILY FOUNDATION
Biomaē+ Daily
The universal foundation. 12 strains, all terrain. For anyone beginning or maintaining a microbiome practice.
WOMEN'S MICROBIOME
Biomaē+ Women
Hormonal microbiome support. Vaginal and gut ecosystem coordination. Calibrated for the female microbiome axis.
DIGESTIVE RESET
Biomaē+ Restore
Post-disruption. High-CFU recolonization after antibiotics or illness. A targeted intensive protocol, not a daily foundation.
Not sure which formula fits your protocol?
Sanaē can review your health goals, current routine, and microbiome history to recommend the right starting point — and adjust as your terrain evolves.